ACDF vs. Cervical Disc Replacement: A Spine Surgeon Explains the Real Differences
ACDF and cervical disc replacement can both relieve pressure on a cervical nerve or spinal cord, but ACDF fuses the level while disc replacement preserves motion, and not every patient is a safe candidate for both.
If you have been told you may need neck surgery, the choice can feel stressful. You may hear one surgeon talk about fusion. Another may mention an artificial disc. Online, it can sound like one operation is “old” and the other is “new.”
That is not how I think about it.
In my practice, I do not think of ACDF and disc replacement as “old versus new.” I think of them as different tools for different anatomy.
This article explains the real differences in plain language.
The Short Answer: Both Surgeries Can Work, But for Different Patients
ACDF stands for anterior cervical discectomy and fusion.
- Anterior means the surgery is done from the front.
- Cervical means the neck part of the spine.
- Discectomy means removing a damaged disc. A disc is the cushion between two spine bones.
- Fusion means joining two bones together so they heal into one solid segment.
Cervical disc replacement may also be called artificial disc replacement, ADR, or cervical arthroplasty. Arthroplasty means replacing a joint or moving part with an artificial device.
Both operations are usually done from the front of the neck.
Both operations remove the disc material or bone spurs that are pressing on a nerve or the spinal cord. A bone spur is extra bone that forms with arthritis or wear. The spinal cord is the main nerve pathway that runs from the brain down the spine.
The main difference is what happens after the pressure is removed:
- ACDF: the disc is removed, and the bones above and below are fused together.
- Disc replacement: the disc is removed, and an artificial disc is placed to keep motion at that level.
Disc replacement is not simply “better fusion.” It is a different tool for a more specific group of patients.
Either surgery may be considered for a clear problem such as a cervical disc herniation. A disc herniation means part of the disc pushes out of place and may press on a nerve.
The right choice depends on your anatomy, MRI findings, symptoms, exam findings, and surgical goals. An MRI, or magnetic resonance imaging scan, is a test that uses magnets to show discs, nerves, the spinal cord, and other soft tissues.
What ACDF Is
What happens during ACDF
During ACDF, the surgeon reaches the spine from the front of the neck.
The damaged disc is removed. The surgeon then takes pressure off the nerve root, spinal cord, or both. A nerve root is the part of a nerve that exits the spine and travels into the arm.
After the pressure is removed, the empty disc space is filled. This may involve:
- A spacer or cage.
- Bone graft, which is bone material used to help fusion.
- A plate and screws in many cases.
The goal is for the bone above and below the removed disc to grow together into one solid segment.
That means motion stops at that level.
Why surgeons still use ACDF
ACDF has a long track record.
It is not an outdated operation. It remains a standard and reliable surgery for many neck spine problems.
Surgeons still use ACDF because it can provide a strong decompression. Decompression means removing pressure from a nerve or the spinal cord.
ACDF is often useful when there is:
- Arthritis.
- Disc collapse.
- Bone spurs.
- Instability.
- Deformity.
- Severe degeneration.
Instability means the bones move too much or in an abnormal way. Degeneration means wear-and-tear change in the discs, joints, or bones.
ACDF can be appropriate for cervical radiculopathy or cervical myelopathy when the surgical target is clear.
Cervical radiculopathy means a pinched nerve in the neck causing arm pain, numbness, tingling, or weakness.
Cervical myelopathy means spinal cord dysfunction from pressure on the spinal cord. It can affect balance, walking, hand coordination, strength, and sensation.
Common reasons ACDF may be favored
ACDF may be favored when the motion segment is no longer healthy enough to preserve. A motion segment means one disc level, including the disc, the bones above and below, and the small joints behind it.
Common reasons include:
- Significant facet joint arthritis.
- Instability or abnormal motion.
- Severe disc space collapse.
- Kyphosis or poor alignment at the level.
- Large bone spurs.
- Ossification or stiff segments.
- Multi-level disease where disc replacement is not appropriate.
- Poor bone quality in some cases.
Facet joints are the small joints in the back of the spine. They help guide motion. Kyphosis means the spine bends forward more than normal. Ossification means tissue has become hardened into bone.
In my practice, fusion is often the more reliable choice when the level is collapsed, stiff, unstable, or dominated by bone spurs rather than a simple soft disc herniation.
What Cervical Disc Replacement Is
What happens during disc replacement
During cervical disc replacement, the diseased disc is removed.
The surgeon relieves pressure on the nerve root or spinal cord. Then an artificial disc is placed between the vertebrae. Vertebrae are the bones of the spine.
The goal is to maintain motion at that level rather than fuse it.
The operation still requires a real decompression. The surgeon still has to remove the correct pressure from the correct nerve or spinal cord area.
Why motion preservation matters
Motion preservation matters because the neck is built to move.
The idea behind disc replacement is to reduce stress transfer to nearby levels. Some studies show lower rates of certain additional surgeries at nearby levels in selected patients.
But preserving motion does not make the entire neck immune to aging or arthritis.
Disc replacement may reduce some adjacent-level stress in selected patients. It does not prevent all future degeneration.
Common reasons disc replacement may be considered
Disc replacement may be considered when the anatomy is favorable.
Common features include:
- One-level or selected two-level cervical disc disease.
- Arm pain from nerve compression due to a disc herniation.
- Preserved disc height and motion.
- Minimal facet arthritis.
- Good alignment.
- No major instability.
- No severe osteoporosis.
- Symptoms and MRI findings match well.
Osteoporosis means weak or brittle bone. Severe osteoporosis can affect how implants hold or settle.
The finding matters most when the disc problem is isolated, the level still moves well, and the joints behind the disc are not already severely arthritic.
For more detail on one-level and two-level cases, see single-level vs two-level cervical disc replacement.
The Main Difference: Fusion Stops Motion, Disc Replacement Preserves Motion
The most important mechanical difference is motion.
ACDF stops motion at the treated level. Cervical disc replacement is designed to keep that level moving.
| Question | ACDF | Cervical Disc Replacement |
|---|---|---|
| Does it remove pressure from nerves/spinal cord? | Yes | Yes |
| Does it preserve motion at that level? | No | Usually yes |
| Is it used for arthritis and instability? | Often | Usually less suitable |
| Is it used for carefully selected disc problems? | Yes | Yes |
| Long-term track record | Very long | Strong but more selective |
| Best for | Broader range of anatomy | More specific candidates |
“Motion-preserving” does not mean “non-invasive.”
Both are real spine surgeries. Both are often done through the front of the neck. Both require careful diagnosis. Both require good patient selection.
If you are comparing procedures based on incision size or technique terms, it may help to read about minimally invasive vs open spine surgery. The label alone does not tell you whether the surgery is right for your anatomy.
Which Surgery Has Better Results?
Pain and nerve symptoms
Both ACDF and disc replacement can improve arm pain when there is true nerve compression that matches your symptoms.
This is especially true when the pain follows a clear nerve pattern. For example, a compressed nerve in the neck may cause pain, tingling, numbness, or weakness down the arm.
Neck pain alone is more complicated.
Neck pain can come from discs, facet joints, muscles, posture, alignment, or several sources at once. Surgery is usually more predictable for arm pain from a clearly pinched nerve than for isolated neck pain.
Outcomes are generally better when three things point to the same level:
- Your symptoms.
- Your physical exam.
- Your imaging.
Adjacent segment disease
Adjacent segment degeneration means nearby discs show wear over time.
Adjacent segment disease means those changes cause symptoms or require treatment.
These are not the same thing.
A fusion can change mechanics at nearby levels. That may increase stress above or below the fused segment.
But aging also matters. Genetics matter. Pre-existing degeneration matters. Some nearby discs may already have been wearing out before surgery.
Disc replacement may reduce some adjacent-level stress in selected patients. Some studies show lower rates of certain additional surgeries at nearby levels.
But disc replacement does not stop the neck from aging.
Reoperation risk
Studies often compare reoperation in two areas:
- The treated level.
- The nearby levels.
Disc replacement may show lower reoperation rates in certain well-selected groups.
ACDF also remains durable, especially when used for the right anatomy.
The key is not to treat population-level data as a personal guarantee. Trial results apply best to patients who look like the people in those studies. Many real-world patients have more arthritis, collapse, instability, or multi-level disease than trial patients.
Who Is Usually a Better Candidate for Cervical Disc Replacement?
A patient may be a disc replacement candidate when:
- The problem is mainly a soft disc herniation or limited disc degeneration.
- There is clear nerve root compression matching arm symptoms.
- The level still moves normally.
- Alignment is acceptable.
- Facet joints are not severely arthritic.
- There is no major instability.
- Bone quality is adequate.
- Disease is limited to one level or carefully selected two-level cases.
The artificial disc needs a reasonably healthy motion segment to work well. If the joints behind the disc are already arthritic or the level is unstable, preserving motion may not be the safest goal.
This is why disc replacement is not the right fit for every MRI that says “disc herniation.”
Who Is Usually a Better Candidate for ACDF?
ACDF may be favored when:
- There are large bone spurs.
- The disc space is severely collapsed.
- The spine is unstable.
- There is significant arthritis of the facet joints.
- There is deformity or kyphosis.
- There is severe narrowing around the spinal cord.
- More than one level is involved and disc replacement is not appropriate.
- A prior surgery or anatomy makes disc replacement less suitable.
ACDF is not a “failure” option.
In many situations, fusion is chosen because it is the more predictable and safer operation for that anatomy.
In my practice, this is one of the most important points to explain. A fusion recommendation does not always mean a surgeon is behind the times. It may mean the level is not healthy enough for motion preservation.
What Your MRI Can and Cannot Tell You
MRI findings that matter in this decision
What I look for on MRI is not just whether a disc is abnormal. I look for whether the abnormality matches the patient’s symptoms and whether the motion segment is healthy enough to preserve.
Important MRI findings include:
- The level of compression.
- Whether compression affects a nerve root, spinal cord, or both.
- Whether the problem is a disc herniation or bone spur.
- Foraminal stenosis.
- Central canal stenosis.
- Spinal cord signal change.
- Disc height collapse.
- Alignment.
- Multi-level degeneration.
- Facet arthritis, if visible or suggested.
- Signs that instability may need X-rays, not just MRI.
Foraminal stenosis means narrowing of the nerve exit tunnel. The foramen is the small opening where the nerve leaves the spine.
Central canal stenosis means narrowing of the main canal that holds the spinal cord.
Spinal cord signal change means the spinal cord looks brighter or abnormal on certain MRI images. It can suggest stress or injury to the spinal cord, but it must be interpreted with symptoms and exam findings.
Why symptoms still matter
An MRI can show narrowing, bulging, arthritis, or degeneration.
But an MRI cannot prove by itself that a finding is causing your symptoms.
Many people have cervical disc degeneration without severe symptoms. Some people have disc bulges or even narrowing on MRI and do not have major pain or weakness.
Surgery is most logical when imaging matches the pattern of:
- Pain.
- Numbness.
- Weakness.
- Reflex changes.
- Myelopathy signs.
Myelopathy signs may include balance trouble, hand clumsiness, numbness in multiple limbs, abnormal reflexes, or weakness.
If your MRI mentions spinal cord compression, it may help to learn more about cervical spinal stenosis and myelopathy.
Trying to understand what your cervical MRI means for the ACDF vs disc replacement decision?
SpineClarity offers a written MRI/case review from a board-certified spine surgeon. Upload your symptoms, MRI report, and relevant records, and receive a plain-language written interpretation with a suggested next-step category. This is not emergency care and does not replace an in-person physician relationship.
Common MRI Phrases That Influence the ACDF vs Disc Replacement Decision
“Disc osteophyte complex”
A disc osteophyte complex means disc bulging plus bone spur formation.
An osteophyte is a bone spur.
This phrase often suggests that the problem is not just a soft disc herniation. If the disease is more bone-spur heavy, the decision may move toward fusion depending on the severity and location.
“Severe foraminal stenosis”
Severe foraminal stenosis means the nerve exit tunnel is very narrow.
This can sometimes be treated with either ACDF or disc replacement. But if the narrowing is mostly from hard bone spurs, ACDF may be more likely.
The reason is simple. The surgeon must fully decompress the nerve. The implant choice matters less than removing the correct pressure.
“Cord compression” or “spinal cord flattening”
Cord compression means something is pressing on the spinal cord.
Spinal cord flattening means the cord shape is being changed by that pressure.
This is an important finding, especially if your symptoms suggest myelopathy. The urgency depends on symptoms, exam findings, and severity.
Cord compression does not automatically mean every case is an emergency. But it should not be ignored if symptoms are progressing.
“Myelomalacia” or “cord signal change”
Myelomalacia means softening or injury-type change in the spinal cord.
Cord signal change means the spinal cord has an abnormal appearance on MRI.
These phrases may suggest that the spinal cord has been under stress. They require careful evaluation in clinical context.
They do not, by themselves, choose ACDF or disc replacement.
“Facet arthropathy”
Facet arthropathy means arthritis of the facet joints.
Facet joints are the small joints in the back of the spine.
Significant facet arthritis can make disc replacement less appropriate. If those joints are already painful or stiff, keeping the level moving may not help. It may even leave the painful joint mechanics in place.
Recovery Differences Patients Should Understand
Early recovery
Both operations can involve:
- Swallowing discomfort.
- Sore throat.
- Neck soreness.
- Activity restrictions.
Swallowing difficulty is called dysphagia.
Many patients notice arm pain improvement relatively early if nerve compression was the main pain generator. A pain generator is the structure causing the pain.
Numbness and weakness may take longer. They may not fully recover, especially if the nerve or spinal cord was compressed for a long time.
Fusion healing vs motion preservation
ACDF requires bone healing across the level.
If the bones do not heal together, this is called nonunion or pseudarthrosis. Pseudarthrosis means a false joint forms where solid bone healing was expected.
Disc replacement does not require the bones to fuse. But the implant still needs to settle, stay stable, and function properly.
Restrictions vary. They depend on surgeon preference, implant type, bone quality, neurologic status, and case details.
Return to work and activity
There is no single timeline that applies to everyone.
Desk work, physical labor, sports, and driving all have different requirements.
Return-to-activity decisions should be individualized by the treating surgeon. The right timing depends on the procedure, your job demands, your neurologic status, and your surgeon’s protocol.
Risks and Tradeoffs of Each Option
Shared risks
Both ACDF and cervical disc replacement are real surgeries.
Shared risks include:
- Infection.
- Bleeding.
- Nerve injury.
- Spinal cord injury.
- Hoarseness or voice changes.
- Swallowing difficulty.
- Persistent pain.
- Need for future surgery.
- Anesthesia risks.
Hoarseness can happen when nerves that help control the vocal cords are irritated. Anesthesia means the medicines used to keep you safe and comfortable during surgery.
ACDF-specific tradeoffs
ACDF-specific tradeoffs include:
- Loss of motion at the fused level.
- Nonunion or pseudarthrosis.
- Hardware-related issues.
- Adjacent segment stress over time.
- Possible need for additional surgery.
Hardware means plates, screws, cages, or other implants used during surgery.
Adjacent segment stress means extra mechanical load may be placed on the disc levels above or below the fusion.
Disc replacement-specific tradeoffs
Disc replacement-specific tradeoffs include:
- Implant wear or failure, though uncommon.
- Heterotopic ossification.
- Implant migration or subsidence.
- Persistent pain if the wrong pain generator was treated.
- Need for revision surgery, sometimes conversion to fusion.
Heterotopic ossification means extra bone forms around the artificial disc. This can reduce motion.
Migration means the implant shifts from its intended position.
Subsidence means the implant settles down into the bone more than expected.
Revision surgery means another operation to correct or change the first surgery.
How Surgeons Think Through the Decision
A surgeon is usually asking:
- What is the exact diagnosis?
- Do symptoms match the MRI?
- Is the problem mainly a nerve root, spinal cord, or neck pain issue?
- Is there instability?
- Is the level still mobile and well-aligned?
- How much arthritis is present?
- Is one level or more than one level involved?
- What are the patient’s goals and risk factors?
- Which operation is most likely to solve the actual problem with the lowest reasonable risk?
In my practice, I do not start with the question, “Which implant is better?” I start with, “What problem are we trying to solve, and which operation best matches that problem?”
The operation should be chosen to solve the patient’s actual problem, not to match a marketing phrase or a fear of fusion.
This is also why it is risky to choose a neck surgery based on advertising terms alone. The same is true for technology terms like robotic-assisted spine surgery. The tool matters less than the diagnosis, anatomy, and surgical plan.
When This Decision Is More Urgent
Some symptoms should not wait for a routine review.
Seek urgent medical evaluation if you have:
- New or worsening arm or hand weakness.
- Trouble with balance or walking.
- Loss of hand coordination, such as dropping objects or difficulty buttoning clothing.
- New bowel or bladder control problems.
- Numbness in multiple limbs.
- Rapidly worsening neurologic symptoms.
- Severe neck pain after trauma.
- Fever, history of cancer, unexplained weight loss, or infection concerns with spine pain.
Seek urgent medical evaluation if you develop new or worsening weakness, trouble walking, loss of hand coordination, numbness in multiple limbs, new bowel or bladder control problems, rapidly worsening neurologic symptoms, severe pain after trauma, or signs of infection or cancer such as fever, unexplained weight loss, or a known cancer history with new spine pain.
This article is educational and cannot determine whether your situation is urgent. If you have progressive neurologic symptoms or signs of spinal cord dysfunction, you should seek prompt in-person medical care.
SpineClarity’s written MRI/case review is not emergency care. If you may have spinal cord dysfunction or rapidly progressive neurologic symptoms, you should seek prompt in-person medical evaluation.
Questions to Ask Your Surgeon
Here are useful questions to bring to your visit:
- What diagnosis are you treating?
- Which level or levels are causing the problem?
- Do my symptoms match my MRI findings?
- Am I a candidate for both ACDF and disc replacement, or only one?
- What MRI findings make disc replacement less appropriate for me?
- Do I have facet arthritis, instability, severe collapse, or kyphosis?
- Is my problem mainly a soft disc herniation or bone spurs?
- What are the risks of doing nothing right now?
- What are the risks of surgery?
- How do you define success in my case?
- What symptoms are most likely to improve?
- What symptoms may not improve?
- How many of these procedures do you perform?
- What would make you recommend fusion over disc replacement?
Bottom Line: The Best Surgery Is the One That Matches the Problem
ACDF and cervical disc replacement are both legitimate operations.
Disc replacement may offer advantages for selected patients. These may include motion preservation and lower rates of certain additional surgeries in some study groups.
ACDF may be safer and more predictable for others. This is especially true when there is severe arthritis, collapse, instability, kyphosis, poor bone quality, or major bony narrowing.
The decision should be based on:
- Diagnosis.
- MRI findings.
- Symptoms.
- Physical exam.
- Anatomy.
- Goals.
- Risk factors.
You should not choose based on marketing language alone.
The most important goal is proper decompression of the correct nerve or spinal cord area. The implant label is secondary.
If your MRI report mentions disc herniation, stenosis, cord compression, or degenerative changes and you are unsure how those findings affect the ACDF vs disc replacement decision, SpineClarity can provide a written MRI/case review from a board-certified spine surgeon. You’ll receive a plain-language explanation and a suggested next-step category. This is not emergency care or a substitute for an in-person physician relationship.
FAQ
Is cervical disc replacement better than ACDF?
Sometimes, for selected patients. But it is not better for everyone.
Disc replacement preserves motion at the treated level. ACDF fuses that level.
Disc replacement is usually a better fit when the disc problem is limited, the level still moves well, and there is little arthritis. ACDF is often better when there is arthritis, instability, collapse, deformity, or severe bony narrowing.
Does ACDF cause the discs above and below to wear out?
ACDF can increase stress at nearby levels.
But that is not the only reason nearby discs may wear out. Aging, genetics, and pre-existing degeneration also matter.
Not every patient develops symptomatic adjacent segment disease after ACDF.
Can I have disc replacement if I have bone spurs?
It depends.
The severity, location, alignment, motion, and facet joint health all matter. Some bone spurs can be removed during decompression. But severe bony narrowing may make fusion more likely.
The main goal is to safely remove pressure from the nerve or spinal cord.
Is cervical disc replacement approved for two levels?
In selected cases, two-level cervical disc replacement may be an option.
This depends on the device, anatomy, surgeon judgment, and regulatory or insurance factors. It does not mean every person with two abnormal discs is a good candidate.
Which surgery is better for cervical myelopathy?
It depends on the cause and anatomy.
Cervical myelopathy means spinal cord dysfunction from compression. ACDF is commonly used when the pressure is from the front of the spine. Disc replacement may be considered only in selected cases.
Progressive myelopathy symptoms need prompt in-person medical care. These include worsening balance, hand clumsiness, weakness, numbness in multiple limbs, or bowel and bladder changes.
Will either surgery help neck pain?
It may, but neck pain is less predictable than arm pain from a pinched nerve.
Neck pain can come from discs, facet joints, muscles, alignment, or several sources at once. Surgery is usually more predictable when there is clear nerve compression causing arm symptoms.
What MRI findings make disc replacement less likely?
Disc replacement may be less appropriate when MRI or X-rays show:
- Severe facet arthritis.
- Instability.
- Severe disc collapse.
- Kyphosis.
- Major bony stenosis.
- Poor bone quality.
- Multi-level advanced degeneration.
These findings do not always rule it out, but they make patient selection more careful.
Can a cervical disc replacement fail and need fusion later?
Yes.
This is uncommon in properly selected patients, but it can happen. Reasons may include implant problems, extra bone formation, persistent pain, migration, subsidence, or progression of disease.
Revision surgery may sometimes involve conversion to fusion.
Related Articles
References
American College of Radiology. (2019). ACR Appropriateness Criteria® Cervical Neck Pain or Cervical Radiculopathy. Journal of the American College of Radiology, 16(5S), S57-S76.
Boden, S. D., McCowin, P. R., Davis, D. O., Dina, T. S., Mark, A. S., & Wiesel, S. (1990). Abnormal magnetic-resonance scans of the cervical spine in asymptomatic subjects. Journal of Bone and Joint Surgery American, 72(8), 1178-1184.
Boselie, T. F. M., Willems, P. C., van Mameren, H., de Bie, R. A., Benzel, E. C., & van Santbrink, H. (2012). Arthroplasty versus fusion in single-level cervical degenerative disc disease. Cochrane Database of Systematic Reviews, (9), CD009173.
Davies, B. M., Mowforth, O. D., Smith, E. K., & Kotter, M. R. N. (2018). Degenerative cervical myelopathy. BMJ, 360, k186.
Davis, R. J., Nunley, P. D., Kim, K. D., et al. (2015). Two-level total disc replacement with Mobi-C cervical artificial disc versus anterior discectomy and fusion: A prospective, randomized, controlled multicenter clinical trial with 4-year follow-up results. Journal of Neurosurgery: Spine, 22(1), 15-25.
Fehlings, M. G., Tetreault, L. A., Riew, K. D., et al. (2017). A clinical practice guideline for the management of patients with degenerative cervical myelopathy. Global Spine Journal, 7(3 Suppl), 70S-83S.
Fountas, K. N., Kapsalaki, E. Z., Nikolakakos, L. G., et al. (2007). Anterior cervical discectomy and fusion associated complications. Spine, 32(21), 2310-2317.
Gornet, M. F., Burkus, J. K., Shaffrey, M. E., et al. (2017). Cervical disc arthroplasty with the Prestige LP disc versus anterior cervical discectomy and fusion at two levels: Results of a prospective, multicenter randomized controlled clinical trial at 24 months. Journal of Neurosurgery: Spine, 26(6), 653-667.
Gornet, M. F., Lanman, T. H., Burkus, J. K., et al. (2016). Cervical disc arthroplasty with the Prestige LP disc versus anterior cervical discectomy and fusion: Seven-year outcomes. International Journal of Spine Surgery, 10, 24.
Hilibrand, A. S., Carlson, G. D., Palumbo, M. A., Jones, P. K., & Bohlman, H. H. (1999). Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis. Journal of Bone and Joint Surgery American, 81(4), 519-528.
Hisey, M. S., Bae, H. W., Davis, R. J., et al. (2016). Prospective, randomized comparison of cervical total disc replacement versus anterior cervical fusion: Results at 5-year follow-up. International Journal of Spine Surgery, 10, 10.
Joaquim, A. F., & Riew, K. D. (2020). Patient selection in cervical disc arthroplasty. Neurospine, 17(1), 5-12.
Kong, L., Ma, Q., Meng, F., Cao, J., Yu, K., & Shen, Y. (2017). The prevalence of heterotopic ossification among patients after cervical artificial disc replacement: A systematic review and meta-analysis. Medicine, 96(24), e7163.
Lawrence, B. D., Hilibrand, A. S., Brodt, E. D., Dettori, J. R., & Brodke, D. S. (2012). Predicting the risk of adjacent segment pathology in the cervical spine: A systematic review. Spine, 37(22 Suppl), S52-S64.
Mummaneni, P. V., Burkus, J. K., Haid, R. W., Traynelis, V. C., & Zdeblick, T. A. (2007). Clinical and radiographic analysis of cervical disc arthroplasty compared with allograft fusion: A randomized controlled clinical trial. Journal of Neurosurgery: Spine, 6(3), 198-209.
Nakashima, H., Yukawa, Y., Suda, K., Yamagata, M., Ueta, T., & Kato, F. (2015). Abnormal findings on magnetic resonance images of the cervical spines in 1211 asymptomatic subjects. Spine, 40(6), 392-398.
North American Spine Society. (2010/2011). Diagnosis and Treatment of Cervical Radiculopathy from Degenerative Disorders: Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care.
Nunley, P. D., Coric, D., Frank, K. A., & Stone, M. B. (2018). Cervical disc arthroplasty: Current evidence and real-world application. Neurosurgery, 83(6), 1087-1106.
Radcliff, K., Davis, R. J., Hisey, M. S., et al. (2017). Long-term evaluation of cervical disc arthroplasty with the Mobi-C cervical disc: A randomized, prospective, multicenter clinical trial. International Journal of Spine Surgery, 11, 31.
Riew, K. D., Ecker, E., Dettori, J. R., & An, H. S. (2010). Anterior cervical discectomy and fusion for the management of axial neck pain in the absence of radiculopathy or myelopathy. Evidence-Based Spine-Care Journal, 1(3), 45-50.
Tetreault, L. A., Karpova, A., & Fehlings, M. G. (2015). Predictors of outcome in patients with degenerative cervical myelopathy undergoing surgical treatment: Results of a systematic review. European Spine Journal, 24 Suppl 2, 236-251.
Zhong, Z. M., Zhu, S. Y., Zhuang, J. S., Wu, Q., & Chen, J. T. (2016). Reoperation after cervical disc arthroplasty versus anterior cervical discectomy and fusion: A meta-analysis. Clinical Orthopaedics and Related Research, 474(5), 1307-1316.